文献类型：期刊文献

英文题名：RESEARCH ON THE RELATIONSHIP BETWEEN AMINO ACIDS AND BIOLOGICAL ACTIVITIES IN VELVET ANTLER USING FACTOR ANALYSIS AN CLUSTER ANALYSIS

作者：Zhou, Libing

第一作者：周利兵

通信作者：Zhou, LB[1]

机构：[1]Guizhou Inst Technol, Sch Chem Engn, Guiyang 550003, Peoples R China

第一机构：贵州理工学院化学工程学院

通信机构：corresponding author), Guizhou Inst Technol, Sch Chem Engn, Guiyang 550003, Peoples R China.|贵州理工学院化学工程学院;贵州理工学院;

年份：2017

卷号：26

期号：5

起止页码：3222-3230

外文期刊名：FRESENIUS ENVIRONMENTAL BULLETIN

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000403134800016)】；

语种：英文

外文关键词：Velvet antler; amino acids; factor analysis; the factor cluster analysis; pharmacological activities; traditional Chinese medicine efficacy; human health; biological activities

摘要：Velvet antler has certain effect on improving the body's immune cells and the regulation of immune system function, nervous system,anti-stress,anti-aging and osteoporosis. It has medicinal applications to treat a wide range of diseases such as tissue wound healing,anti tumor, cardiovascular disease,et al. Therefore, the research on the relationship between pharmacological activities and amino acids in velvet antler is of great significance. The objective of this study was to comprehensively evaluate 17 kinds of amino acids in 5 varieties of velvet antlers and study on the relationship between the amino acids and traditional Chinese medicine efficacy for humans.The factor analysis and the factor cluster analysis methods were used to analyze the data of amino acids in the sika velvet antler, cervus elaphus linnaeus, flower horse hybrid velvet antler, apiti (elk) velvet antler, male reindeer velvet antler and find out the relationship between 17 kinds of amino acids including aspartic acid Xi, threonine X-2, serine X-3, glutamate X-4, proline X-5, glycine X-6, alanine X-7, valine X-8, methionine X-9, isoleucine X-10, leucine X-11, tyrosine X-12, phenylalanine X-13, lysine acid X-14, histidine X-15, arginine acid X-16, tryptophan acid X-17. Using MATLAB 2013 and SPSS software, the factor analysis and the factor cluster analysis research was made on the relationship between amino acids and biological activities in velvet antler.The first commonality factor F-1 had greater load on the indexes of threonine X-2, glutamate X-4,proline X-6,alanine X-7,methi onine X-9,isoleucine X-10,pheny-lalanine X-13,lysine acid X-14,arginine acid X-16, and the second commonality factor F-2 had greater load on the indexes of leucine X-11, tyrosine X-12, histidine X-15,and the third commonality factor F-3 had greater load on the indexes of aspartic acid X-1, serine X-3, glycine X-6, valine X-8, tryptophan acid X-17. Different varieties of velvet antlers (including sika velvet antler, cervus elaphus linnaeus, flower horse hybrid velvet antler, apiti(elk) velvet antler and male reindeer velvet antler) in China contained the contents of 17 kinds of amino acids in the order from high to low: flower horse hybrid velvet antler >cervus elaphus linnaeus>sika velvet antler>male reindeer velvet antler>apiti(elk) velvet antler. In terms of content of amino acids, flower horse hybrid velvet antler medicinal materials were the best quality, followed by cervus elaphus linnaeus medicinal materials, apiti(elk) velvet antler medicinal materials were worst. Based on the factor analysis and the factor cluster analysis, a model for evaluating traditional Chinese medicine quality was constructed. These studies show that velvet antler not only has a very strong role at the health-care aspect, but also has high medicinal value, for humans, suggesting that people can absorb amino acids needed from velvet antler. These studies provide the scientific base and theoretical foundation for the future large-scale rational relation development of velvet antler resources as well as the relationship between the amino acids and tradi-tional Chinese medicine efficacy for the human.