文献类型：期刊文献

英文题名：Chemical Composition, Antioxidant, Antimicrobial and Cholinesterase Inhibitory Activities of Essential Oils from the Leaves and Rhizomes of Acorus macrospadiceus (Yamamoto) F. N.Wei et Y. K. Li

作者：Ma, Chao Zhu, Guofei Li, Tingting Zhao, Tianming

第一作者：马超

通信作者：Zhao, TM[1]

机构：[1]Guizhou Inst Technol, Coll Food & Pharmaceut Engn, Guiyang 550003, Peoples R China;[2]Guizhou Univ, Coll Liquor & Food Engn, Guiyang 550025, Peoples R China

第一机构：贵州理工学院食品药品制造工程学院

通信机构：corresponding author), Guizhou Inst Technol, Coll Food & Pharmaceut Engn, Guiyang 550003, Peoples R China.|贵州理工学院食品药品制造工程学院;贵州理工学院;

年份：2021

卷号：24

期号：6

起止页码：1323-1332

外文期刊名：JOURNAL OF ESSENTIAL OIL BEARING PLANTS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000746216500012)】；

基金：This research was funded by the Science and Technology Program of Guizhou Province (No. Qian Ke He Ji Chu [2017]1075), the High-level Talent Research Funding Project of Guizhou Institute of Technology (XJGC20161206) and the Science and Technology Innovation Program for Returnee in Guizhou Province (QRXMZZHT [2015]18).

语种：英文

外文关键词：Acorus macrospadiceus; antimicrobial; cholinesterase inhibitory; essential oil; estragole

摘要：Acorus macrospadiceus is an aromatic herb that is widely distributed in southwest China. However, reports on the biological activities of its essential oil (EO) are limited. In the present study, the chemical composition, antioxidant, antimicrobial and cholinesterase inhibitory activities were determined for essential oils extracted from the leaves and rhizomes of this species. The essential oils were extracted by hydrodistillation and analysed by gas chromatography/mass spectrometry (GC/MS) and gas chromatography with a flame ionization detector (GC/FID). Antioxidant activity was examined using DPPH, ABTS and FRAP assays. Antimicrobial activity was evaluated by determining the minimum inhibitory concentrations (MICs) and minimum microbiocidal concentrations (MMCs). Acetylcholinesterase and butyrylcholinesterase inhibitory activities of the essential oils were also tested to evaluate the potential effect of the EOs on neurodegenerative disease. A total of 15 and 19 components were identified in the leaf and rhizome EOs, representing 99.24% and 98.35% of the total composition, respectively. Estragole was found to be the most abundant compound at 98.14% and 94.69% of the leaf and rhizome EOs, respectively. The essential oils displayed weak antioxidant and acetylcholinesterase inhibitory activities. The essential oils showed higher inhibitory effects against Candida albicans than other strains, with a MIC of 3.13 mg/mL, indicating possible use in the treatment of Candida infections.