文献类型：期刊文献

英文题名：Synthesis, antifungal and insecticidal activity of novel [1,2,4]triazolo[4,3-a]pyridine derivatives containing a sulfide substructure

作者：Xu, Fang-Zhou Shao, Jia-Hui Zhu, Yun-Ying Liu, Li-Wei Zhao, Yong-Hui Shan, Wei-Li Wang, Yan-Yan Wu, Jian Yang, Song Xue, Wei

第一作者：Xu, Fang-Zhou

通信作者：Wu, J[1];Xue, W[1]

机构：[1]Guizhou Univ, State Key Lab Breeding Base Green Pesticide & Agr, Key Lab Green Pesticide & Agr Bioengn, Minist Educ,Res & Dev Ctr Fine Chem, Guiyang 550025, Peoples R China;[2]Zaozhuang Univ, Coll Life Sci, Zaozhuang 277100, Peoples R China;[3]Guizhou Inst Technol, Sch Chem Engn, Guiyang 550001, Peoples R China;[4]Minist Agr, Inst Control Agrochem, Beijing 100125, Peoples R China

第一机构：Guizhou Univ, State Key Lab Breeding Base Green Pesticide & Agr, Key Lab Green Pesticide & Agr Bioengn, Minist Educ,Res & Dev Ctr Fine Chem, Guiyang 550025, Peoples R China

通信机构：corresponding author), Guizhou Univ, State Key Lab Breeding Base Green Pesticide & Agr, Key Lab Green Pesticide & Agr Bioengn, Minist Educ,Res & Dev Ctr Fine Chem, Guiyang 550025, Peoples R China.

年份：2017

卷号：71

期号：4

起止页码：729-739

外文期刊名：CHEMICAL PAPERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000398722600003)】；

基金：This work was supported by the National Natural Science Foundation of China (21562012, 21302025, 21162004), the Special Foundation of S&T for Outstanding Young Talents in Guizhou (No. 2015-15), and the Introduction of Talent Research Projects of Guizhou University (No. J[2014]2056).

语种：英文

外文关键词：[1,2,4]Triazolo[4,3-a]pyridine; Sulfide; Synthesis; Antifungal activity; Insecticidal activity

摘要：A series of [1,2,4]triazolo[4,3-a]pyridine derivatives bearing a sulfide substructure was designed, synthesized and characterized via H-1 center dot NMR, C-13 center dot NMR, IR and elemental analyses. Bioassay Results indicated some of the derivatives displayed good fungicidal activity on Rhizoctonia cerealis, moderated insecticidal activity against Plutella xylostella and good insecticidal activity on Helicoverpa armigera. The inhibitory effects of compounds 4g and 4u against Rhizotonia cerealis were 70.9% at 50 mu g mL(-1); the IC50 values of compounds 4d and 4s against Plutella xylostella were 43.87 and 50.75 mu g mL(-1), respectively. And the IC50 values of compounds 4d, 4q, and 4s on Helicoverpa armigera were 58.3, 77.14 and 65.31 mu g mL(-1), respectively, which were better than that of commercial chlorpyrifos (103.77 mu g mL(-1)).