文献类型：期刊文献

英文题名：Design, synthesis and antibacterial activity of amide-containing dehydroabietic acid derivatives

作者：Bai, Song Feng, Shuang Li, Miao Wan, Suran Fang, Wang Tang, Shouyin Wei, Xian Chen, Lijun Zhang, Miaohe Wu, Rong

第一作者：Bai, Song;柏松

通信作者：Wu, R[1]

机构：[1]Guizhou Ind Polytech Coll, Guiyang 550008, Peoples R China;[2]Guizhou Inst Technol, Sch Chem Engn, Guiyang, Peoples R China;[3]Guizhou Univ, State Key Lab Breeding Base Green Pesticide & Agr, Key Lab Green Pesticide & Agr Bioengn, Minist Educ, Guiyang, Peoples R China

第一机构：Guizhou Ind Polytech Coll, Guiyang 550008, Peoples R China

通信机构：corresponding author), Guizhou Ind Polytech Coll, Guiyang 550008, Peoples R China.

年份：2025

外文期刊名：MOLECULAR CRYSTALS AND LIQUID CRYSTALS

收录：;EI(收录号：20253419030978);Scopus(收录号：2-s2.0-105013771165);WOS:【SCI-EXPANDED(收录号:WOS:001554162400001)】；

基金：The research is financially supported by the Science and Technology Planning Project of Guizhou Province [Grant No. Qian Ke He Ji Chu ZK [2022]Zhong Dian 025], High School Science and Technology Talent Support Project of Guizhou Province, China [Grant No. Qian Jiao He KY Zi [2021]037], Guizhou Industry Polytechnic College Science and Technology Innovation Team Project [Grant No. 2023CXTD03], the academic new seedling cultivation and exploration and innovation project of Guizhou Institute of Technology [No. GZLGXM-20], Guizhou Provincial Department of Education Youth Science and Technology Talent Growth Project [Grant No. Qian Jiao Ji [2024]293 Hao], Guizhou Industry Polytechnic College Faculty-level Research Project [Grant No. 2023ZK10 & Grant No. 2023ZK11], The Young Science and Technology Talents Development Program of Education Department of Guizhou Province [Grant NO. Qian Jiao He KY Zi [2022]346 Hao], High-Level Talent Initial Funding of Guizhou Industry Polytechnic College [Grant No. 2023-RC-01], The Opening Foundation of the Key Laboratory of Green Pesticide and Agricultural Bioengineering, the Ministry of Education, Guizhou University [Grant No. Qian Jiao Ji [2022]433], Guizhou Industry Polytechnic College Faculty-level Research Project [grant no. 2024zk18 & 2024zk19].

语种：英文

外文关键词：Antibacterial activity; changes in cell morphology; dehydroabietic acid derivatives

摘要：This study designed and synthesized a series of dehydroabietic acid derivatives containing amide groups. Bioactivity tests demonstrated that these compounds exhibited remarkable antibacterial properties. Notably, compounds P1 and P3 exhibited promising in vitro antibacterial activity against Xanthomonas oryzae pv. oryzicola (Xoc), with half-maximal effective concentrations values of 52.8 and 51.4 mg/L, respectively. In addition, compound P9 exhibited an excellent antibacterial effect against Xanthomonas axonopodis pv. citri, achieving 69.6% inhibition at a concentration of 100 mg/L. Furthermore, P3 effectively inhibited Xoc growth by increasing bacterial membrane permeability, leading to changes in cell morphology.