文献类型：期刊文献

英文题名：Chemical composition and antioxidant, antimicrobial, enzyme inhibitory, and antiproliferative activities of Lindera communis leaf essential oil

作者：Zhao, Tianming Qin, Wenxiang Kang, Songwen Shu, Xinhe Tai, You Fan, Guang

第一作者：赵天明

通信作者：Zhao, TM[1]

机构：[1]Guizhou Inst Technol, Coll Food & Pharmaceut Engn, Guiyang 550003, Peoples R China

第一机构：贵州理工学院食品药品制造工程学院

通信机构：corresponding author), Guizhou Inst Technol, Coll Food & Pharmaceut Engn, Guiyang 550003, Peoples R China.|贵州理工学院食品药品制造工程学院;贵州理工学院;

年份：2024

外文期刊名：JOURNAL OF ESSENTIAL OIL BEARING PLANTS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001158096000001)】；

基金：This work was funded by the High-level Talent Research Funding Project of Guizhou Institute of Technology (XJGC20161206).

语种：英文

外文关键词：Lindera communis; Essential oil; Germacrene D; MIC; Tyrosinase; Butyrylcholinesterase; Antiproliferative

摘要：Lindera communis is a medicinal and aromatic plant widely distributed in China. Its leaves are rich in essential oil (EO), but the reports on biological activities of the leaf EO are limited. This study aimed to analyze the chemical composition of L. communis leaf EO and evaluate its different biological activities. The leaf EO was obtained by hydro-distillation and analyzed by GC-MS and GC-FID. 53 compounds were identified, representing 96.80% of the total composition. The major compounds included germacrene D (28.34%), bicyclogermacrene (21.07%), germacrene B (6.14%) and spathulenol (5.73%). SC50 values of L. communis leaf EO in DPPH and ABTS assays were 252.36 and 34.25 mg/mL, respectively, indicating inactivity in antioxidant effect. MICs of L. communis leaf EO against Bacillus cereus, Listeria monocytogenes, Staphylococcus aureus and Staphylococcus epidermidis were 25 mg/mL. Of four enzymes, inhibitory effects on tyrosinase and butyrylcholinesterase were observed, with kojic acid equivalent (KAE) and galanthamine equivalent (GE) values as 22.89 +/- 1.38 mg KAE/g of EO and 67.13 +/- 0.99 mg GE/g of EO, respectively. L. communis leaf EO also demonstrated strong antiproliferative effects on MCF-7 and HepG2 cells. At the concentration of 500 mu g/mL, the cell viability of MCF-7 cells was only 4.86%. L. communis leaf EO could find its possible use in cosmetic and pharmaceutical industries.