文献类型：期刊文献

中文题名：艾纳香生物碱微胶囊制备工艺优化及稳定性研究

英文题名：The Study on Preparation and Stability of Alkaloid of Blumea balsamifera(L.) DC

作者：李小红 刘莹 李安 吴德智

第一作者：李小红

机构：[1]贵州理工学院

第一机构：贵州理工学院

年份：2018

卷号：0

期号：2

起止页码：165-169

中文期刊名：食品工业

外文期刊名：The Food Industry

收录：北大核心:【北大核心2017】；

基金：贵州省"耀创客"众创空间项目;贵州省大学生创新创业项目

语种：中文

中文关键词：艾纳香生物碱;微胶囊;Box—Behnken响应曲面试验;稳定性

外文关键词：alkaloid ofBlumea balsamifera （L.） DC; microcapsules; Box-Behnken response surface methodology; stability

摘要：采用壳聚糖(CS)控制p H饱和水溶液法制备艾纳香生物碱微胶囊,以生物碱包埋率为指标,以芯壁比、搅拌时间和搅拌温度为考察因素,进行单因素及Box-Behnken响应曲面试验优化微胶囊配方。结果表明:艾纳香生物碱微胶囊最佳的制备工艺为芯壁比16.2、搅拌时间59 min和搅拌温度40℃,得出的生物碱包埋率为61.21%±0.21%,经电镜法观察其形态规则,分布均匀。稳定性试验结果表明制备的微胶囊在高温、强光下包埋率稳定,高湿条件下包埋率下降,为艾纳香生物碱的进一步开发利用提供参考。
Flavonoids ofBlumea balsamifera （L.） DC microcapsules were prepared by Chitosan （CS） saturated water solution method. Effects of ratio of wall to core, stirring time and stirring temperature were studied via the single factor methodologies, and then the optimal formula was determined by Box-Behnken response surface methodology. The results showed that the optimal formula was ratio of wall to core 16.2, stirring time 59 min and stirring temperature 40℃. The rate of retention was 61.21%±0.21%. And the morphology was regular observed by electron microscope. The results of stability test showed that the embedding rate was stable under high temperature and strong light, which was conductive to further study.