文献类型：期刊文献

英文题名：Discovery of novel ascorbic acid derivatives and other metabolites in fruit of Rosa roxburghii Tratt through untargeted metabolomics and feature-based molecular networking

作者：Zhang, Yaqi Bian, Xiqing Yan, Guanyu Sun, Baoqing Miao, Wen Huang, Mingzheng Li, Na Wu, Jian-Lin

第一作者：Zhang, Yaqi

机构：[1] State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, China; [2] Department of Allergy and Clinical Immunology, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, National Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China; [3] College of Food and Pharmaceutical Engineering, Guizhou Institute of Technology, Guizhou, Guiyang, China

第一机构：State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, China

年份：2023

卷号：405

外文期刊名：Food Chemistry

收录：EI(收录号：20224513094301);Scopus(收录号：2-s2.0-85141466136)

语种：英文

外文关键词：Ascorbic acid - Biomolecules - Glucose - Liquid chromatography - Mass spectrometry - Metabolites

摘要：Fruit of Rosa roxburghii Tratt (FRR) is widely used in functional food industry while short of metabolites research. Herein, we firstly identified 251 metabolites in FRR based on untargeted liquid chromatography-mass spectrometry (LC-MS) approach. Then, 42 differential compounds were sought out to avoid the confusing use of FRR and fruit of R. sterilis S. D. Shi (FRS), and FRR was evaluated exhibiting higher biofunction potential. Moreover, a quantitative LC-MS approach was established to determine the contents of 3 ascorbyl hexosides, and FRR with higher contents should be better source than FRS. Additionally, 17 ascorbic acid (AA) derivatives formed by conjugation of ascorbyl unit with organic acids, flavonoids, or glucuronic acid were also discovered in FRR through characteristic ions of AA and feature-based molecular networking (FBMN), enlightening that AA derivatives were not limited to ascorbyl glycosides. This study provided abundant metabolites information of FRR, laying the basis for exploitation of FRR. ? 2022 Elsevier Ltd