文献类型：期刊文献

英文题名：Metal-Free, Hindered, Regioselective Access to Multifunctional Groups Diarylamines via SNAr Substitution of P-Nitroso Aromatic Methyl Ether by Arylamines

作者：Zou, Shuliang Zhang, Yazhou Wu, Qin Zhao, Tianming Li, Yutao Liu, Bing Ma, Xianguo

第一作者：邹树良

机构：[1] School of Food and Drug Manufacturing Engineering, Guizhou Institute of Technology, Doctor Road, Dangwu Town, Gui'an New District, Guiyang, 550003, China; [2] School of Chemical Engineering, Guizhou Institute of Technology, Doctor Road, Dangwu Town, Gui'an New District, Guiyang, 550003, China; [3] School of Pharmacy, Guizhou University of Traditional Chinese Medicine, No. 4, Dongqing Road, Huaxi District, Guiyang, 550025, China

第一机构：贵州理工学院

年份：2023

外文期刊名：Chemistry - A European Journal

收录：EI(收录号：20240215355591);Scopus(收录号：2-s2.0-85181678284)

语种：英文

外文关键词：Amines - Aromatic compounds - Regioselectivity

摘要：Multifunctional groups diarylamines, an innovative product, efficiently produced from arylamines and p-nitrosoanisole derivatives by intermolecular SNAr under weak acid conditions. This SNAr proceeds under mild reaction conditions, and more significantly, the substrates involved do not necessarily require strong electron-withdrawing groups. Moreover, this SNAr is characterized by resistance to space crowding, tolerance to halogen and nitroso functional groups, and high regioselectivity. Mechanistic observations suggest that the SNAr is the result of the transfer of the positive charge center of the protonated nitroso group to the p-methoxy group. ? 2023 Wiley-VCH GmbH.