文献类型：期刊文献

英文题名：Advances in chromone-based reactants in the ring opening and skeletal reconstruction reaction: access to skeletally diverse salicyloylbenzene/heterocycle derivatives

作者：Guo, Dong-Gui Wang, Hui-Juan Zhou, Ying Liu, Xiong-Li

第一作者：Guo, Dong-Gui

通信作者：Liu, XL[1]

机构：[1]Guizhou Univ, Natl & Local Joint Engn Res Ctr Exploitat Homol R, Guiyang 550025, Guizhou, Peoples R China;[2]Guizhou Inst Technol, Coll Food & Pharmaceut Engn, Guiyang 550003, Guizhou, Peoples R China;[3]Guizhou Univ Chinese Med, Coll Pharmaceut Sci, Guiyang 550025, Guizhou, Peoples R China

第一机构：Guizhou Univ, Natl & Local Joint Engn Res Ctr Exploitat Homol R, Guiyang 550025, Guizhou, Peoples R China

通信机构：corresponding author), Guizhou Univ, Natl & Local Joint Engn Res Ctr Exploitat Homol R, Guiyang 550025, Guizhou, Peoples R China.

年份：2022

卷号：20

期号：23

起止页码：4681-4698

外文期刊名：ORGANIC & BIOMOLECULAR CHEMISTRY

收录：;EI(收录号：20222312197458);Scopus(收录号：2-s2.0-85131232842);WOS:【SCI-EXPANDED(收录号:WOS:000800316400001)】；

基金：We highly appreciate the financial support from the National Natural Science Foundation of China NSFC (22061006) and the Project of Guizhou Province (ZK[2021]520, [2020]4Y205 and [2020]1Z074).

语种：英文

摘要：Salicyloylbenzene/heterocycles are privileged scaffolds found in many natural products and bioactive molecules. Numerous useful approaches for the preparation of these privileged scaffolds have been developed in recent years. Among these approaches, chromone-based reactants have demonstrated their importance in the synthesis of these salicyloylbenzene/heterocycle scaffolds with structural complexity and potential biological appeal. In this review, the recent advances in the synthesis of salicyloylbenzene/heterocycles are summarized and discussed according to the chromone-based reactants which could be achieved in one step via ring-opening and skeletal reconstruction reactions. Both the mechanisms and the applications of the corresponding products in organic and medicinal chemistry are also described.