文献类型：期刊文献

英文题名：Divinyl BODIPY derivative: Synthesis, photophysical properties, crystal structure, photostability and bioimaging

作者：Yang, Liutao Liu, Ying Liu, Wei Ma, Chunping Zhang, Chun Li, Yang

第一作者：Yang, Liutao;杨柳涛

通信作者：Yang, LT[1]

机构：[1]Guizhou Inst Technol, Coll Mat & Met Engn, Guiyang 550003, Guizhou, Peoples R China;[2]Guizhou Inst Technol, Coll Chem Engn, Guiyang 550003, Guizhou, Peoples R China;[3]Collaborat Innovat Ctr Special Funct Mat Guizhou, Guiyang, Peoples R China

第一机构：贵州理工学院材料与冶金工程学院

通信机构：corresponding author), Guizhou Inst Technol, Coll Mat & Met Engn, Guiyang 550003, Guizhou, Peoples R China.|贵州理工学院材料与冶金工程学院;贵州理工学院;

年份：2015

卷号：25

期号：24

起止页码：5716-5719

外文期刊名：BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

收录：;Scopus(收录号：2-s2.0-84947272191);WOS:【SCI-EXPANDED(收录号:WOS:000365032800012)】；

基金：The authors wish to acknowledge the financial support to the project from Science and Technology Department of Guizhou Province-Guizhou Institute of Technology Joint Fund [No. (2015)7101], key project supported by Guizhou Province Training Program of Innovation and Entrepreneurship for Undergraduates (No. 201414440008), Guizhou Institute of Technology (Nos. XJGC20140602, XJGC20141103), and National Natural Science Foundation of China (Item No. 51503046). We also thank Prof. Di Wu and Xiangge Zhou in Sichuan University for guidance.

语种：英文

外文关键词：BODIPY; Crystal structure; Bathochromism; Cell imaging

摘要：4,4-Difluoro-3,5-bis(3,3-dimethyl-1-butenyl)-8-anthryl-4-bora-3a,4a-diaza-s-indacene (1), a symmetric fluorescent difluoroboron dipyrromethene dye, was produced in Knoevenagel reaction involving 4,4-difluoro-3,5-bis(methyl)-8-anthryl-4-bora-3a,4a-diaza-s-indacene (2) and pivaldehyde. Its crystal structure was determined by single crystal X-ray diffraction analysis, and the photophysical properties were investigated. The BODIPY 1 exhibits significant bathochromic shifts in both absorption and fluorescence spectrum compared with the BODIPY 2. In addition, the BODIPY 1 exhibited small energy gaps (2.11 eV). The extensive pi conjugation is responsible for their red-shifted emission. Cell imaging experiments demonstrated its potential application as a biological fluorescent probe due to its excellent imaging contrast. (C) 2015 Elsevier Ltd. All rights reserved.