文献类型：期刊文献

中文题名：大孔吸附树脂纯化右旋龙脑的工艺研究

英文题名：Study on Purification Process of d-Borneol by D101 Macroporous Adsorption Resin

作者：黄丽荣 龙文 骆衡

第一作者：黄丽荣

机构：[1]贵州理工学院食品药品制造工程学院,贵州贵阳550003;[2]贵州省中国科学院天然产物化学重点实验室,贵州贵阳550014

第一机构：贵州理工学院食品药品制造工程学院

年份：2021

卷号：49

期号：3

起止页码：36-38

中文期刊名：广州化工

外文期刊名：GuangZhou Chemical Industry

基金：贵州省科技合作计划项目(No.黔科合LH字[2016]7092)。

语种：中文

中文关键词：右旋龙脑;D101大孔吸附树脂;纯化

外文关键词：d-borneol;D101 macroporous adsorptionresin;purification

摘要：研究洗脱剂乙醇体积分数、洗脱流速、上样液浓度对D101大孔吸附树脂纯化右旋龙脑效果的影响,确立右旋龙脑纯化工艺。通过单因素考察实验和正交实验,确立的最佳工艺条件为:洗脱剂乙醇体积分数为80%,洗脱流速为3.5 BV/h,上样液浓度为0.55 g/mL。在此条件下,右旋龙脑收率可达81.6%,纯度为98.32%。考察的因素对分离效果的影响程度为:洗脱剂乙醇的体积分数>洗脱流速>上样液浓度。建立的右旋龙脑精制工艺操作简便、收率高,适合扩大化生产。
The influence of volume fraction of alcohol as desorption solution,flow rate,and mass concentration of sample on d-borneol purification effect by D101 macroporous adsorption resin was studied,and the purification process of d-borneol was established.Results of single factor experiment and orthogonal experiment indicated the optimal conditions were as follows:the volume fraction of alcohol as desorption solution was 80%,the flow rate was 3.5 BV/h,and the mass concentration of sample was 0.55 g/mL.Under these conditions,the yield of d-borneol was 81.6%,and the content of the product was 98.32%.The influence degree of the factors investigated on purification effect was the volume fraction of alcohol as desorption solution>flow rate>mass concentration of sample.