文献类型：期刊文献

英文题名：Discovery of novel ascorbic acid derivatives and other metabolites in fruit of Rosa roxburghii Tratt through untargeted metabolomics and feature-based molecular networking

作者：Zhang, Yaqi Bian, Xiqing Yan, Guanyu Sun, Baoqing Miao, Wen Huang, Mingzheng Li, Na Wu, Jian-Lin

第一作者：Zhang, Yaqi

通信作者：Li, N[1];Wu, JL[1]

机构：[1]Macau Univ Sci & Technol, State Key Lab Qual Res Chinese Med, Taipa, Macau, Peoples R China;[2]Guangzhou Med Univ, Dept Allergy & Clin Immunol,Affiliated Hosp 1, Guangzhou Inst Resp Hlth,Natl Ctr Resp Med, State Key Lab Resp Dis,Natl Clin Res Ctr Resp Dis, Guangzhou, Peoples R China;[3]Guizhou Inst Technol, Coll Food & Pharmaceut Engn, Guiyang, Guizhou, Peoples R China

第一机构：Macau Univ Sci & Technol, State Key Lab Qual Res Chinese Med, Taipa, Macau, Peoples R China

通信机构：corresponding author), Macau Univ Sci & Technol, State Key Lab Qual Res Chinese Med, Taipa, Macau, Peoples R China.

年份：2023

卷号：405

外文期刊名：FOOD CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001119513400001)】；

基金：This work was supported by the Science and Technology Development Fund, Macau SAR [grant number FDCT 0025/2021/A1], and Science and Technology Project of Guizhou Province, China, Grant/Award Number: [2021]174.

语种：英文

外文关键词：Chemical profiling; Differential analysis; Ascorbyl hexosides; Novel AA derivatives

摘要：Fruit of Rosa roxburghii Tratt (FRR) is widely used in functional food industry while short of metabolites research. Herein, we firstly identified 251 metabolites in FRR based on untargeted liquid chromatography-mass spectrometry (LC-MS) approach. Then, 42 differential compounds were sought out to avoid the confusing use of FRR and fruit of R. sterilis S. D. Shi (FRS), and FRR was evaluated exhibiting higher biofunction potential. Moreover, a quantitative LC-MS approach was established to determine the contents of 3 ascorbyl hexosides, and FRR with higher contents should be better source than FRS. Additionally, 17 ascorbic acid (AA) derivatives formed by conjugation of ascorbyl unit with organic acids, flavonoids, or glucuronic acid were also discovered in FRR through characteristic ions of AA and feature-based molecular networking (FBMN), enlightening that AA derivatives were not limited to ascorbyl glycosides. This study provided abundant metabolites information of FRR, laying the basis for exploitation of FRR.